JavaScript seems to be disabled in your browser.
You must have JavaScript enabled in your browser to utilize the functionality of this website.

Axon Medchem

All

Home
Products
- Shop By Category
- Featured Products
- Shop By Alphabet
  - A
  - B
  - C
  - D
  - E
  - F
  - G
  - H
  - I
  - J
  - K
  - L
  - M
  - N
  - O
  - P
  - Q
  - R
  - S
  - T
  - U
  - V
  - W
  - X
  - Y
  - Z
  - #
Support
- - Customer Support
  - Customer Services
Contact
- About Axon Medchem
- Contact Us

Home
Products
Receptors
GPCR
Other
SBI-115

SBI-115

Based on 10 reference(s) in Google Scholar 8 10 10

Axon 4374

CAS [882366-16-7]

MF C14H13ClN2O4S
MW 340.78

Purity: 99%
Soluble in DMSO

Recently added

SBI-115

Description

SBI-115 is a TGR5 antagonist which decreases cell proliferation, cholangiocyte spheroid growth and cAMP levels in cystic cholangiocytes.

KEYWORDS: SBI-115 | Supplier | TGR5 antagonist | SBI 115 | SBI115 | CAS [882366-16-7] | Biliary System | Bile acids | Antagonist | Receptors | Hepatic cystogenesis | Polycystic liver disease | PLD | G protein-coupled bile acid receptor | GPCR19 | Takeda G protein receptor 5

TV Masyuk et al. TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling. Hepatology. 2017 Oct;66(4):1197-1218.

Miscellaneous

TGR5 antagonist

Chemical name

1,3-Tolyl 5-chloro-2-(ethylsulfonyl)-4-pyrimidinecarboxylate

Parent CAS No.

[882366-16-7]

Order

Size	Unit Price	Stock
10 mg	€90.00	In Stock
50 mg	€270.00	In Stock

Need more? Bulk Inquiry

Please wait...