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Axon 4371
CAS [3026986-17-1]
MF C20H16N4O4MW 376.37
SJ3149 is a potent and selective degrader of CK1α protein, which inhibited MOLM-13 cell growth with an IC50 value of 13 nM and reduced CK1α abundance with DC50 value of 3.7 nM and Dmax 95%.
KEYWORDS: SJ3149 | Supplier | CK1α degrader | SJ 3149 | SJ-3149 | CAS [3026986-17-1] | Non Selective (Phosphorylation substrates) | CK | Degrader | Enzymes | Molecular-glue degrader | Hematologic and solid tumors
3-(5-(1,2-Benzisoxazol-3-ylamino)-1-oxo-2-isoindolinyl)-2,6-piperidinedione
[3026986-17-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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