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PF-543 hydrochloride

Based on 78 reference(s) in Google Scholar 8 10 78

Axon 4360

CAS [1706522-79-3]

MF C27H31NO4S·HCl
MW 502.07

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water, DMSO and EtOH
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PF-543 hydrochloride

Description

Cell-permeant reversible inhibitor of SphK1 (IC50 value 2.0 nM; Ki value 3.6 nM). PF-543 hydrochloride is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform. The citrate salt form PF-543 citrate (Axon 2350) is also available.

KEYWORDS: PF-543 hydrochloride | Supplier | SphK1 inhibitor | PF543 | PF 543 | CAS [1415562-82-1] | CAS [1706522-79-3] | Sphingosine | SphK | SphK1 | Inhibitor | Enzymes | Ceramide | S1P | cell permeant

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5 mg €90.00 In Stock
25 mg €300.00 In Stock
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2 x 5 mg €140.00 In Stock
2 x 25 mg €460.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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