A much-improved version of ErSO (Axon 3594), ErSO-DFP is an anticipatory unfolded protein response (a-UPR) activator. ErSO-DFP has enhanced selectivity for estrogen receptor alpha-positive (ERα+) cancer cells with a wider selectivity window than ErSO. ErSO-DFP displays antitumor activity and leads to profound regression of MCF-7 tumors in mice model.

KEYWORDS: ErSO-DFP | Supplier | a-UPR activator | CT-ERSOR | CAS [2768139-76-8] | Unfolded Protein Response (Non Selective) | Estrogen (ER) | Activator | Receptors