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TT-012

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 4314

CAS [1164471-33-3]

MF C19H15N3O4
MW 349.34

Purity: 99%
Soluble in DMSO and EtOH

Recently added

TT-012

Description

TT-012 is a potent MITF dimer disruptor which specifically binds to dynamic MITF and destroys the latter’s dimer formation and DNA-binding ability.

KEYWORDS: TT-012 | Supplier | MITF dimer disruptor | TT012 | TT 012 | CAS [1164471-33-3] | DNA-RNA | MITF | Disruptor | Transcription Factors | Melanoma | Microphthalmia transcription factor

Z Liu et al. A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res. 2023 Jan;33(1):55-70.

Cell Signaling & Oncology Transcription Factors MITF TF class 1.3

Potent MITF dimer disruptor

Chemical name

N-(6-((E)-2-(2-Furyl)ethenylcarbonylamino)-2-pyridyl)-(E)-3-(2-furyl)acrylamide

Parent CAS No.

[1164471-33-3]

Order

Size	Unit Price	Stock
10 mg	€120.00	In Stock
50 mg	€420.00	In Stock

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2733	ML329	Inhibitor of the MITF molecular pathway		€110.00

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