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Axon 4307
CAS [2201048-82-8]
MF C16H10F4N6MW 362.29
Zagociguat is a first potent brain-penetrant soluble guanylate cyclase (sGC) stimulator with EC50 values of 66 nM (GloSensor luciferase assay) and 46 nM (cGMP assay of rat primary neurons). Zagociguat improved neuronal activity, mediated neuroprotection, and increased cognitive performance in preclinical models.
KEYWORDS: Zagociguat | Supplier | sGC stimulator | CY6463 | IW6463 | CY 6463 | CY-6463 | IW-6463 | IW 6463 | CAS [2201048-82-8] | GTP | sGC | Stimulator | Enzymes | Neurodegenerative disease | Nitric oxide | Huntington’s disease | Alzheimer's disease
5-(7-((2-Fluorophenyl)methyl)-1,3a-diaza-5-indenyl)-3-(trifluoromethyl)-1H-1,2,4-triazole
[2201048-82-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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