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Axon 4284
CAS [2215927-89-0]
MF C22H21N5O2MW 387.44
EI-52 is an inhibitor of ERK-MYD88 interaction with IC50 values of 3.1 and 14.7 µM for MYD88/ERK1 and MYD88/ERK2 interaction inhibition by HTRF, respectively. ERK-MYD88 interaction inhibition induces an HRI-mediated integrated stress response (ISR), resulting in immunogenic apoptosis specific to cancer cells.
KEYWORDS: EI-52 | Supplier | ERK-MYD88 inhibitor | EI52 | EI 52 | CAS [2215927-89-0] | MAPK | ERK | Inhibitor | Enzymes | RAS/MAP kinase pathway | Neoplasia | RAS signaling cascade
N-(6-Methoxy-3-pyridyl)-2-(4-(dimethylamino)phenyl)-1H-1,3-benzimidazole-5-carboxamide
[2215927-89-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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