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Axon 4264
CAS [2984543-29-3]
MF C20H19F5N8OMW 482.41
ART-446 is a potent small molecule CHK2 (Checkpoint kinase 2) inhibitor (IC 50 = 9 nM). It exhibits promising potential in enhancing the therapeutic effects of Olaparib (Axon 1464) and Irinotecan (Axon 3370).
KEYWORDS: ART-446 | Supplier | CHK2 inhibitor | ART446 | ART 446 | CT-ART446 | CAS [2984543-29-3] | DNA-RNA | CHK | Inhibitor | Enzymes
3-Amino-6-(5-fluoro-2-(1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl)pyridin-4-yl)-N-((3S,5S)-5-fluoropiperidin-3-yl)pyrazine-2-carboxamide
[2984543-29-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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