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Axon 4199
CAS [2289690-31-7]
MF C26H16ClF9N2O2MW 594.86
MYCi361 is a MYC inhibitor (Kd value of 3.2 µM) which disrupts MYC/MAX complexes, promotes MYC T58 phosphorylation and MYC degradation. MYCi361 suppressed in vivo tumor growth in mice, increased tumor immune cell infiltration, upregulated PD-L1 on tumors, and sensitized tumors to anti-PD1 immunotherapy.
KEYWORDS: MYCi361 | Supplier | MYC inhibitor | NUCC0196361 | CAS [2289690-31-7] | DNA-RNA | c-MYC | Inhibitor | Transcription Factors | anti-PD1 immunotherapy
6-(4-Chlorobenzyloxy)-3-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-3',5'-bis(trifluoromethyl)biphenyl-2-ol
[2289690-31-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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