HSL119

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 4186

CAS [2231745-56-3]

MF C30H27F3N6O
MW 544.57

  • Purity: 99%
  • Soluble in 0.1N HCl(aq), DMSO and EtOH
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HSL119

Description

HSL119 is a potent and selective first-generation HUNK inhibitor (IC50 value of ∼1.7μM in JIMT-1 cells). HSL119 has significant efficacy toward treating HER2+ breast cancer, even those that are resistant to HER2 inhibitors.

KEYWORDS: HSL119 | Supplier | HUNK inhibitor | HSL 119 | HSL-119 | CAS [2231745-56-3] | HER2 pathway | Rubicon | AMPK | Inhibitor | Enzymes | HER2+ breast cancer | Human epidermal growth factor receptor 2 | Autophagy | Hormonally upregulated neu-associated kinase

Potent and selective first-generation HUNK inhibitor

Chemical name

3-((8-Amino-1,7-naphthyridin-5-yl)ethynyl)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

Parent CAS No.

[2231745-56-3]

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10 mg €140.00 In Stock
50 mg €500.00 In Stock
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2 x 10 mg €200.00 In Stock
2 x 50 mg €800.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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