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Axon 4186
CAS [2231745-56-3]
MF C30H27F3N6OMW 544.57
HSL119 is a potent and selective first-generation HUNK inhibitor (IC50 value of ∼1.7μM in JIMT-1 cells). HSL119 has significant efficacy toward treating HER2+ breast cancer, even those that are resistant to HER2 inhibitors.
KEYWORDS: HSL119 | Supplier | HUNK inhibitor | HSL 119 | HSL-119 | CAS [2231745-56-3] | HER2 pathway | Rubicon | AMPK | Inhibitor | Enzymes | HER2+ breast cancer | Human epidermal growth factor receptor 2 | Autophagy | Hormonally upregulated neu-associated kinase
3-((8-Amino-1,7-naphthyridin-5-yl)ethynyl)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
[2231745-56-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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