KU-0058948

Based on 20 reference(s) in Google Scholar 8 10 20

Axon 4179

CAS [763111-49-5]

MF C21H21FN4O2
MW 380.42

  • Purity: 99%
  • Soluble in 0.1N HCl(aq), DMSO and EtOH

KU-0058948

Description

Potent and specific PARP inhibitor (IC50: 3.4 nM for PARP1); KU-0058948 activates transfected extracellular signal-regulated kinase 8 (ERK8) in cells and induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro. The hydrochloride salt form, KU-0058948 hydrochloride (Axon 2001) is also available.

Keywords: KU-0058948 | Supplier | PARP1 inhibitor | KU0058948 | KU 0058948 | CAS [763111-49-5] | [2108829-86-1] | [1379676-61-5] | DNA-RNA | PARP | Inhibitor | Enzymes

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Size Unit Price Stock
10 mg €135.00 In Stock
50 mg €505.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €220.00 In Stock
2 x 50 mg €760.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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