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Axon 4177
CAS [2922531-69-7]
MF C19H17F3N4OSMW 406.43
MR-2088 is a best-in-class, potent and selective ULK1/2 inhibitor with a ULK1 binding/activity of 2 nM. MR-2088 blocks autophagy flux and synergizes with Trametinib (Axon 1761) to provide antiproliferative effects in NSCLC.
KEYWORDS: MR-2088 | Supplier | ULK1/2 inhibitor | MR2088 | MR 2088 | CAS [2922531-69-7] | Non Selective (Phosphorylation substrates) | ULK | ULK1 | ULK2 | Inhibitor | Enzymes | Autophagy | UNC-51-like kinase
4-(2-(1,2,5,6-Tetrahydropyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-(2,2,2-trifluoroethyl)thiophene-2-carboxamide
[2922531-69-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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