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Verubecestat - MK8931

Based on 67 reference(s) in Google Scholar 8 10 67

Axon 4166

CAS [1286770-55-5]

MF C17H17F2N5O3S
MW 409.41

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO and EtOH

Verubecestat

Description

Verubecestat is a first-in-class, potent, orally bioavailable high-affinity BACE1 inhibitor with Ki values of 2.2 and 0.38 nM for BACE1 and BACE2, respectively. Verubecestat shows high selectivity for BACE1 over other key aspartyl proteases.

Keywords: Verubecestat | Supplier | BACE 1 inhibitor | MK8931 | MK 8931 | MK-8931 | CAS [1286770-55-5] | [1875153-95-9] | [2055309-33-4] | [2095432-65-6] | Amyloids | BACE | Inhibitor | Enzymes | Alzheimer's Disease | β-site amyloid precursor protein cleaving enzyme 1

Order
Size Unit Price Stock
5 mg €80.00 In Stock
25 mg €200.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €120.00 In Stock
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2957 BACE-2 Inhibitor Potent and highly selective BACE 2 inhibitor €140.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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