GS-9973 - Entospletinib

Based on 8 reference(s) in Google Scholar 8 10 8

Axon 4153

CAS [1229208-44-9]

MF C23H21N7O
MW 411.47

  • Purity: 98%
  • Soluble in DMSO
Recently added



GS-9973 is an oral and selective inhibitor of spleen tyrosine kinase (Syk) with an IC50 of 7.7 nM. It inhibits the activity of Syk, which inhibits B-cell receptor (BCR) signaling and leads to an inhibition of tumor cell activation, migration, adhesion and proliferation.

KEYWORDS: GS-9973 | Supplier | Syk inhibitor | Entospletinib | GS-9973 | GS-9973 | CT-GS9973 | CAS [1229208-44-9] | B-Cell transformation | Spleen tyrosine kinase (Syk) | Inhibitor | Enzymes

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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