Ulixertinib hydrochloride - BVD-523 hydrochloride | VRT752271 hydrochloride

Based on 104 reference(s) in Google Scholar 8 10 104

Axon 4151

CAS [1956366-10-1]

MF C21H23Cl3N4O2
MW 469.79

  • Purity: 99%
  • Optical purity: >99% e.e.
  • Soluble in DMSO
Recently added

Ulixertinib hydrochloride

Description

Birinapant is a cell permeable, orally bioavailable, synthetic bivalent small molecule peptido mimetics of second mitochondrial-derived activator of caspases (SMAC) and potent and selective inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins with Kd values of 45 nM and <1 nM for XIAP and cIAP1, respectively. SMAC mimetics Birinapant and LCL-161 (Axon 3902) are also negative regulators of HIV-1 transcription, promoting reversal of viral latency.

Keywords: Birinapant | Supplier | Bivalent Smac mimetic and potent antagonist for XIAP and cIAP1 inhibitor | TL32711 | TL-32711 | TL 32711 | CT-BIRI | CAS [1260251-31-7] | Caspase | IAP | Inhibitor | Proteins

Potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases

Chemical name

(S)-4-(5-chloro-2-iisopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide hydrochloride

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[869886-67-9]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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