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Axon 4150
CAS [1260251-31-7]
MF C42H56F2N8O6MW 806.94
Birinapant is a cell permeable, orally bioavailable, synthetic bivalent small molecule peptido mimetics of second mitochondrial-derived activator of caspases (SMAC) and potent and selective inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins with Kd values of 45 nM and <1 nM for XIAP and cIAP1, respectively. SMAC mimetics Birinapant and LCL-161 (Axon 3902) are also negative regulators of HIV-1 transcription, promoting reversal of viral latency.
Keywords: Birinapant | Supplier | Bivalent Smac mimetic and potent antagonist for XIAP and cIAP1 inhibitor | TL32711 | TL-32711 | TL 32711 | CT-BIRI | CAS [1260251-31-7] | Caspase | IAP | Inhibitor | Proteins
(2S,2'S)-N,N'-((2S,2'S)-1,1'-((3S,3'S,5R,5'R)-5,5'-(6,6'-Difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis(methylene)bis(3-hydroxypyrrolidine-5,1-diyl))bis(1-oxobutane-2,1-diyl))bis(2-(methylamino)propanamide)
[1260251-31-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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