JavaScript seems to be disabled in your browser. You must have JavaScript enabled in your browser to utilize the functionality of this website.
There are no items in your shopping cart
Featured Products
Axon 4148
CAS [934660-93-2]
MF C21H21F3IN3O2MW 531.31
GDC-0973 is an orally bioavailable, potent and selective small-molecule inhibitor of mitogen-activated protein kinase 1 (MAP2K1 or MEK1). It blocks the catalytic activity of MEK1, resulting in inhibition of extracellular signal-related kinase 2 (ERK2) phosphorylation and activation, and decreased tumor cell proliferation. GDC-0976 is used, in combination with PLX4032 (Axon 1624), in the treatment of unresectable or metastatic melanoma with a BRAF V600E or V600K mutation.
Keywords: GDC-0973 | Supplier | MEK1 inhibitor | Cobimetinib | RG7420 | XL518 | GDC0973 | GDC 0973 | RG-7420 | RG 7420 | XL-518 | XL 518 | CT-G0973 | CAS [934660-93-2] | MAPK | MEK | Inhibitor | Enzymes
(S)-(3,4-Difluoro-2-(2-fluoro-4-iodophenylamino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone
[934660-93-2]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
* Required Fields