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Axon 4144
CAS [1353550-13-6]
MF C26H26N6O2SMW 486.59
Olmutinib is a third-generation, orally bioavailable and irreversible Tyrosine Kinase Inhibitor, potently and selectively targeting EGFR mutants with Ki values of ~10 nM (in vitro cell assays, against sensitizing (Del19, L858R) and resistance (T790M) EGFR mutations), highly selective over Wt EGFR (Ki = >2000nM, >200-fold selectivity).
Keywords: Olmutinib | Supplier | EGFR inhibitor | BI 1482694 | HM71224 | BI 1482694 | BI 1482694 | HM71224 | HM71224 | CT-HM712 | CAS [1353550-13-6] | EGF | EGFR | Inhibitor | Receptors
N-(3-(2-(4-(4-Methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide
[1353550-13-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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