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Axon 4140
CAS [1821428-35-6]
MF C26H31N5O3MW 461.56
AZD0156 is potent, selective, and orally available inhibitor of ATM kinase. AZD0156 prevents DNA damage checkpoint activation, disrupts DNA damage repair, induces tumor cell apoptosis, and leads to cell death in ATM-overexpressing tumor cells. In addition, AZD0156 also sensitizes tumor cells to chemo- and radiotherapy.
Keywords: AZD0156 | Supplier | ATM inhibitor | AZD-0156 | AZD 0156 | CAS [1821428-35-6] | DNA-RNA | ATM | Inhibitor | Enzymes
8-(6-(3-(Dimethylamino)propoxy)pyridin-3-yl)-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one
[1821428-35-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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