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Axon 4110
CAS [2407854-18-4]
MF C27H22F2N6O3MW 516.50
BMS-502 is a first-in-class potent and selective dual DGKα/ζ lipid kinase inhibitor with IC50 values of 5 nM and 2 nM for DGKα and DGKζ, respectively. BMS-502 demonstrated dose-dependent immune stimulation in the mouse OT-1 model.
Keywords: BMS-502 | Supplier | DGKα/ζ inhibitor | BMS502 | BMS 502 | CAS [2407854-18-4] | Diacylglycerol (DAG) | DGK | Inhibitor | Enzymes | Programmed cell death protein 1 | Immune checkpoint blockade therapy | T cell receptor
8-(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)-5-methyl-7-nitro-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile
[2407854-18-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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