PITB

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Axon 4107

CAS [3054913-44-6]

MF C14H10FNO6
MW 307.23

  • Purity: 98%
  • Soluble in DMSO and EtOH
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PITB

Description

PITB is a high affinity, orally bioavailable transthyretin (TTR) aggregation inhibitor with optimal pharmacokinetic properties. PITB binds with high affinity to TTR, effectively inhibiting tetramer dissociation and aggregation of both the wild-type protein and the two most prevalent disease-associated TTR variants.

KEYWORDS: PITB | Supplier | TTR aggregation inhibitor | CAS [3054913-44-6] | Transthyretin | Inhibitor | Proteins | Amyloid disease | Transthyretin amyloidosis | ATTR | Pharmacokinetically Improved TTR Binder

High affinity, orally bioavailable TTR aggregation inhibitor

Chemical name

(3-Fluoro-5-hydroxyphenyl)(4-hydroxy-3-methoxy-5-nitrophenyl)methanone

Parent CAS No.

[3054913-44-6]

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5 mg €130.00 In Stock
25 mg €460.00 In Stock
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2 x 5 mg €220.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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