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OTS964 hydrochloride

Based on 11 reference(s) in Google Scholar 8 10 11

Axon 4097

CAS [1338545-07-5]

MF C23H24N2O2S.HCl
MW 428.97

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in water, DMSO and EtOH

OTS964 hydrochloride

Description

OTS964 hydrochloride is a TOPK small molecular inhibitor, binding to the enzyme potently and selectively with IC50 at lower nM. The inhibition causes a cytokinesis defect and the subsequent apoptosis of cancer cells in vitro as well as in xenograft models of human lung cancer. The free base OTS-964 (Axon 3876) is also available.

Keywords: OTS964 hydrochloride | Supplier | TOPK inhibitor | OTS 964 | OTS-964 | CAS [1338545-07-5] | [1338542-14-5] | Non Selective (Serine peptide bonds) | TOPK | CDK | Inhibitor | Enzymes

TOPK (T–lymphokine-activated killer cell–originated protein kinase) inhibitor

Chemical name

(R)-9-(4-(1-(Dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one hydrochloride

Parent CAS No.

[1338542-14-5]

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Size Unit Price Stock
5 mg €120.00 In Stock
25 mg €420.00 In Stock
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Size Unit Price Stock
2 x 5 mg €180.00 In Stock
2 x 25 mg €640.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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