DFPQ - AP-06-202

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 4082

CAS [911678-60-9]

MF C20H20F2N4
MW 354.40

  • Purity: 98%
  • Soluble in DMSO and EtOH
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DFPQ

Description

DFPQ is a potent and selective β-arrestin-biased negative allosteric modulator (NAM) for the β2-adrenergic receptor. DFPQ selectively inhibits β-arrestin interaction with the β2AR without affecting β-agonist-promoted cAMP production. DFPQ attenuates functional desensitization of the β2AR in airway smooth muscle, augmenting the ability of β-agonists to sustain bronchorelaxation and inhibition of cell migration under conditions of chronic β-agonist treatment.

KEYWORDS: DFPQ | Supplier | β2 NAM | AP-06-202 | AP 06-202 | AP06-202 | CAS [911678-60-9] | (Nor-)Adrenaline | Adrenoceptor β2 | NAM | Receptors | Asthma | Airway disease

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Size Unit Price Stock
10 mg €90.00 In Stock
50 mg €330.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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