AZ5104

Based on 36 reference(s) in Google Scholar 8 10 36

Axon 4074

CAS [1421373-98-9]

MF C27H31N7O2
MW 485.58

  • Purity: 99%
  • Soluble in DMSO and EtOH
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AZ5104

Description

AZ5104 is an active circulating metabolite of AZD9291 (Axon 2342). It shares the similar overall activity profile with AZD9291, but is more potent against mutant EGFR forms, while hitting the wild-type EGFR form at a lower concentration thus demonstrating a smaller selectivity margin compared with the parent. Like AZD9291, AZ5104 displays potent antitumor activities both in vitro and in vivo.

Keywords: AZ5104 | Supplier | EGFR inhibitor | AZ-5104 | AZ 5104 | CT-AZ5104 | CAS [1421373-98-9] | EGF | EGFR | Inhibitor | Receptors

EGFR inhibitor

Chemical name

N-(5-(4-(1H-Indol-3-yl)pyrimidin-2-ylamino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[1421373-98-9]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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