MCC950 sodium salt - CP456773 | CRID3

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Axon 4052

CAS [256373-96-3]

MF C20H23N2NaO5S
MW 426.46

  • Purity: 98%
  • Soluble in water, DMSO and EtOH
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MCC950 sodium salt

Description

MCC950 sodium salt is a highly potent and selective inhibitor of the NLRP3 inflammasome with IC50 values of 7.5 nM and 8.1 nM in mouse bone marrow derived macrophages (BMDM) and human monocyte derived macrophages (HMDM), respectively. MCC950 specifically inhibits NLRP3 but not AIM2, NLRC4 or NLRP1 activation.

Keywords: MCC950 sodium salt | Supplier | NLRP3 inhibitor | CP456773 | CRID3 | MCC 950 | MCC-950 | CP 456773 | CP-456773 | CRID 3 | CAS [256373-96-3] | [210826-40-7] | NF-κB pathway | NLR | Inhibitor | Receptors | Inflammatory diseases | Multiple sclerosis | Type 2 diabetes | Atherosclerosis | NOD-like receptor

Highly potent and selective NLRP3 inflammasome inhibitor

Chemical name

Sodium (1,2,3,5,6,7-hexahydros-indacen-4-ylcarbamoyl)(4-(2-hydroxypropan-2-yl)furan-2-ylsulfonyl)amide

Parent CAS No.

[210826-40-7]

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10 mg €120.00 In Stock
50 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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