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IDO2 inhibitor compound 22

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 4041

CAS [2803768-09-2]

MF C21H21BrN10O3
MW 541.36

  • Purity: 98%
  • Soluble in DMSO
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IDO2 inhibitor compound 22

Description

IDO2 inhibitor compound 22 is a first selective IDO2 inhibitor with an IC50 value of 112 nM. Treatment with IDO2 inhibitor compound 22 alleviated disease severity and reduced inflammatory cytokines in both the collagen-induced arthritis (CIA) mice model and adjuvant arthritis (AA) rat model.

KEYWORDS: IDO2 inhibitor compound 22 | Supplier | IDO2 inhibitor | CAS [2803768-09-2] | L-Kynurenine | IDO | Inhibitor | Enzymes | Rheumatoid arthritis | Autoimmune disease

First selective IDO2 inhibitor

Chemical name

(Z)-N-((1-(2-(4-(N-(3-Bromobenzyl)-N'-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-ylamino)ethyl)-1H-1,2,3-triazol-4-yl)methyl)picolinamide

Parent CAS No.

[2803768-09-2]

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5 mg €260.00 In Stock
25 mg €780.00 In Stock
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2 x 5 mg €400.00 In Stock
2 x 25 mg €1,200.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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