BMS-777607

Based on 51 reference(s) in Google Scholar 8 10 51

Axon 4040

CAS [1025720-94-8]

MF C25H19ClF2N4O4
MW 512.89

BMS-777607

Description

A potent, selective and orally bioavailable c-Met inhibitor.

Cell Signaling & Oncology c-MET RTK class X; EC 2.7.10.1

potent, selective and orally bioavailable c-Met inhibitor

N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide

Sold in collaboration with Chemietek

[1025720-94-8]

Axon ID	Name	Description
1581	SU 11274	ATP-competitive inhibitor of c-MET	€90.00
1582	Foretinib	c-MET and VEGFR2 tyrosine kinase inhibitor	€90.00
1583	PF 04217903 mesylate	c-MET tyrosine kinase Inhibitor	€80.00
1660	Crizotinib	c-MET Inhibitor; NPM-ALK inhibitor	€70.00
1819	Cabozantinib S-malate	Inhibitor of multiple receptor tyrosine kinases, specifically MET and VEGFR2	€60.00
1838	ARQ 197	c-MET tyrosine kinase Inhibitor	€90.00
1914	SGX 523	ATP-competitive inhibitor of c-MET	€120.00
1916	AMG 208	Inhibitor of c-MET receptor tyrosine kinase (RTK)	€95.00
1959	Golvatinib	Potent and orally available inhibitor of c-MET (HGFR) and VEGFR2	€90.00
2368	Amuvatinib	RTK inhibitor which effectively inhibits PDGFR, c-Kit and c-Met	€105.00
2553	LY 2801653	Orally bioavailable multi-kinase inhibitor with potent activity against c-MET	€120.00
3423	Capmatinib	Highly potent, selective, ATP competitive and orally bioavailable c-MET inhibitor	€80.00
3864	Volitinib dihydrochloride	ATP-competitive small molecule c-Met kinase inhibitor	Inquire
3945	AMG-337	Potent and exquisitely selective inhibitor of wild-type and some mutant forms of c-Met	Inquire
3946	Altiratinib	Balanced inhibitor for MET, TIE2 (TEK), and VEGFR2 (KDR) kinases	Inquire
3975	MGCD265 dihydrochloride	Orally active, potent MET/SMO dual inhibitor	€130.00