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Axon 4037
CAS [1001264-89-6]
MF C24H32ClN5O2MW 458.00
GDC-0068 is a potent, APT-competitive and orally available small molecule pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively, and with selectivity over more than other 200 screened kinases. It displays robust antitumor activity with activation of PI3K-Akt-mTOR pathway.
KEYWORDS: GDC-0068 | Supplier | Akt inhibitor | Ipatasertib | RG7440 | GDC0068 | GDC 0068 | RG-7440 | RG 7440 | CT-G0068 | CAS [1001264-89-6] | Phosphatidylinositol | Akt | Inhibitor | Enzymes
(S)-2-(4-Chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one
[1001264-89-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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