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Axon 4036
CAS [2326521-71-3]
MF C32H35ClFN7O2MW 604.12
MRTX849 is an orally available, potent, mutation-selective, and irreversible covalent inhibitor of KRAS-G12C, currently under evaluation as antitumor therapies by modulating KRAS-dependent signal transduction as a single agent, or in combination of with SHP2 inhibitor TNO155.
KEYWORDS: MRTX849 | Supplier | KRAS-G12C inhibitor | Adagrasib | MRTX-849 | MRTX 849 | CAS [2326521-71-3] | GTP | KRAS | Inhibitor | Enzymes
2-((S)-4-(7-(8-Chloronaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-1-(2-fluoroacryloyl)piperazin-2-yl)acetonitrile
[2326521-71-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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