MRTX849 - Adagrasib

Product has not been rated yet

Axon 4036

CAS [2326521-71-3]

MF C32H35ClFN7O2
MW 604.12

  • Purity: 99%
  • Optical purity: 99% d.e.
  • Soluble in DMSO



MRTX849 is an orally available, potent, mutation-selective, and irreversible covalent inhibitor of KRAS-G12C, currently under evaluation as antitumor therapies by modulating KRAS-dependent signal transduction as a single agent, or in combination of with SHP2 inhibitor TNO155.

KEYWORDS: MRTX849 | Supplier | KRAS-G12C inhibitor | Adagrasib | MRTX-849 | MRTX 849 | CT-MRTX849 | CAS [2326521-71-3] | GTP | KRAS | Inhibitor | Enzymes

Potent, mutation-selective, and irreversible covalent inhibitor of KRAS-G12C

Chemical name


Source information

Sold in collaboration with Chemietek

Parent CAS No.


The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...