TAK-632

Based on 27 reference(s) in Google Scholar 8 10 27

Axon 4033

CAS [1228591-30-7]

MF C27H18F4N4O3S
MW 554.52

  • Purity: 99%
  • Soluble in DMSO
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TAK-632

Description

TAK-632 is a potent and selective pan-RAF inhibitor targeting B-RAF V600E (IC50 = 2.4 nM), C-RAF (IC50 1.4 nM) and VEGFR (IC50 = 160 nM), displaying significant cellular activity against mutated BRAF and mutated NRAS cancer cell lines.

KEYWORDS: TAK-632 | Supplier | RAF inhibitor | TAK632 | TAK 632 | CT-TAK632 | CAS [1228591-30-7] | MEK | RAF | Inhibitor | Enzymes

Potent and selective pan-RAF inhibitor

Chemical name

N-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)cyclopropanecarboxamide

Source information

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Parent CAS No.

[1228591-30-7]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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