Deflazacort

Based on 326 reference(s) in Google Scholar 8 10 326

Axon 4022

CAS [14484-47-0]

MF C25H31NO6
MW 441.52

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO and EtOH

Deflazacort

Description

Deflazacort is a glucocorticoid and inactive prodrug which is converted rapidly to the active metabolite 21-desacetyldeflazacort.

A Markham et al. Deflazacort. A review of its pharmacological properties and therapeutic efficacy. Drugs. 1995 Aug;50(2):317-33.

H Möllmann et al. Pharmacokinetic/pharmacodynamic evaluation of deflazacort in comparison to methylprednisolone and prednisolone. Pharm Res. 1995 Jul;12(7):1096-100.

Immunology Pain & Inflammation NR3C Glucocorticoid (GR)

Glucocorticoid prodrug

Chemical name

[2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-Hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,14,17-trien-8-yl]-2-oxoethyl] acetate

Parent CAS No.

[14484-47-0]

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Deflazacort

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