Calcium influx inducer compound 634 enhanced the release of extracellular vesicles (EVs) with immunostimulatory potency via induction of Ca2+ influx. Moreover, compound 634 enhanced the number of EVs released by murine bone marrow-derived dendritic cells (mBMDCs) and increased costimulatory molecule expression on parental mBMDCs in a SOCE-dependent manner.

Keywords: Calcium influx inducer compound 634 | Supplier | Ca influx inducer | CAS [882291-37-4] | Calcium | Non Selective | Inducer | Ion Channels | Immune studies | Vaccine | Innate immunity | ISRE | EV-based vaccine | Store-operated Ca2+ entry | SOCE