Uprosertib - GSK2141795 | GSK795

Based on 38 reference(s) in Google Scholar 8 10 38

Axon 3958

CAS [1047634-65-0]

MF C18H16Cl2F2N4O2
MW 429.25

  • Purity: 99%
  • Optical purity: 100% e.e.
  • Soluble in DMSO

Uprosertib

Description

Uprosertib is an orally bioavailable, selective and ATP-competitive pan-Akt (PKB) inhibitor, potently inhibiting Akt 1, 2, 3, and Akt 1 E17K mutation with IC50s of 0.066 nM, 2 nM, 1.4 nM, 1.5 nM, and 0.2nM, respectively.

KEYWORDS: Uprosertib | Supplier | Akt inhibitor | GSK2141795 | GSK795 | GSK-2141795 | GSK 2141795 | GSK-795 | GSK 795 | CT-GSK214 | CAS [1047634-65-0] | Phosphatidylinositol | Akt | Inhibitor | Enzymes

Selective and ATP-competitive pan-Akt (PKB) inhibitor

Chemical name

N-((S)-1-Amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan-2-carboxamide

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[1047634-65-0]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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