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Senicapoc - ICA-17043

Based on 77 reference(s) in Google Scholar 8 10 77

Axon 3951

CAS [289656-45-7]

MF C20H15F2NO
MW 323.34

Purity: 99%
Soluble in DMSO and EtOH

Senicapoc

Description

Senicapoc is a potent and selective antagonist of the Gardos (KCa3.1) channel with an IC50 value of 11 nM.

KEYWORDS: Senicapoc | Supplier | Gardos channel antagonist | ICA-17043 | ICA17043 | ICA 17043 | CAS [289656-45-7] | Potassium | KCa3.1 | Antagonist | Ion Channels | Sickle cell disease | KCNN4

JW Stocker et al. ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice. Blood. 2003 Mar 15;101(6):2412-8.

Cardiovascular CNS Pain & Inflammation KCa3.1 KCNN4

Potent and selective antagonist of the Gardos channel

Chemical name

2,2-Bis(4-fluorophenyl)-2-phenylacetamide

Parent CAS No.

[289656-45-7]

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Size	Unit Price	Stock
10 mg	€65.00	In Stock
50 mg	€165.00	In Stock

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