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Enzymes
Transferases
Kinases (Serine-Threonine Specific Protein)
p70-RSK
Bisindolylmaleimide V

Bisindolylmaleimide V - Ro 31-6045

Based on 83 reference(s) in Google Scholar 8 10 83

Axon 3940

CAS [113963-68-1]

MF C21H15N3O2
MW 341.36

Purity: 99%
Soluble in DMSO and EtOH

Bisindolylmaleimide V

Description

Bisindolylmaleimide V is an in vivo S6K inhibitor (IC50 value of 8 μM) and also the inactive analogue of the protein kinase C inhibitor Ro 31-8220.

Keywords: Bisindolylmaleimide V | Supplier | S6K inhibitor | Ro 31-6045 | Ro31-6045 | Ro-31-6045 | CAS [113963-68-1] | Non Selective (Ribosomal proteins) | p70-RSK | Inhibitor | Enzymes | Mitogen-stimulated protein kinase p70s6k/p85s6k

N Marmy-Conus et al. Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70(s6k)/p85(s6k): implications for the analysis of S6K signalling. FEBS Lett. 2002 May 22;519(1-3):135-40.

Cell Signaling & Oncology PI3K-Akt-mTOR EC 2.7.11.1 p70-RSK

S6K inhibitor

Chemical name

3,4-Di(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione

Parent CAS No.

[113963-68-1]

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Size	Unit Price	Stock
5 mg	€120.00	In Stock
25 mg	€420.00	In Stock

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