Based on 3 reference(s) in Google Scholar 8 10 3

Axon 3934

CAS [1618658-88-0]

MF C28H28N6O4
MW 512.56

  • Purity: 99%
  • Soluble in DMSO



CC-671 is a potent and selective dual inhibitor of TTK (Human Protein Kinase Monopolar Spindle 1 (hMps1)) / CLK2 (CDC2-like Kinase), with IC50 values of 5 nM and 3 nM, respectively, a unique feature targeting both TTK (mitotic exit) and CLK2 (mRNA splicing). It displays a strong single agent in vivo antitumor efficacy in multiple TNBC (Triple negative breast cancer) xenograft models.

KEYWORDS: CC-671 | Supplier | TTK inhibitor | CC671 | CC 671 | CT-CC671 | CAS [1618658-88-0] | Non Selective (Mitotic spindle checkpoint) | MPS1 Kinase | Inhibitor | Enzymes

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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