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Axon 3931
CAS [1022958-60-6]
MF C28H35ClN6O3MW 539.07
CEP-28122 is a highly potent, selective and orally active ALK inhibitor (Ezymatic IC50: 1.9 nM, 3 nM, Cellular IC50: 30 nM), Cellular IC50 in 75% murine: 300 nM), displaying a favorable pharmaceutical and pharmacokinetic profile and robust and selective pharmacologic efficacy against ALK-positive human cancer cells and tumor xenograft models in mice.
KEYWORDS: CEP-28122 | Supplier | ALK inhibitor | CEP28122 | CEP 28122 | CT-CEP281 | CAS [1022958-60-6] | | Non Selective | ALK | Inhibitor | Enzymes
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
[1022958-60-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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