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Featured Products
Axon 3927
CAS [2291360-73-9]
MF C25H27N3O3MW 417.51
NVP-DKY709 is a first-in-class selective CRBN glue degrader of IKZF2 that spares IKZF1/3. In vivo, treatment with NVP-DKY709 delayed tumor growth in mice with a humanized immune system and enhanced immunization responses in cynomolgus monkeys.
KEYWORDS: NVP-DKY709 | Supplier | IKZF2 degrader | NVP-DKY-709 | NVP-DKY 709 | CAS [2291360-73-9] | Ubiquitin | IKZF | Degrader | Transcription Factors | Cancer immunotherapy | Helios | Solid tumor | CRBN E3 ligase
3-(5-(1-Benzylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
[2291360-73-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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