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Axon 3923
CAS [1061318-81-7]
MF C22H30N6O2SMW 442.58
CUDC-305 is an orally bioavailable inhibitor of Heat Shock Proteins, displaying high affinity for HSP90α/β (about 100 nM in IC50) and HSP90 complex derived from cancer cells (IC50= 48.8 nM). Exhibits high oral bioavailability (96.0%) and selective retention in tumor (half-life, 20.4 hours) compared with normal tissues. BBB Penetrant.
KEYWORDS: CUDC-305 | Supplier | HSP90 inhibitor | DEBIO-0932 | CUDC305 | CUDC 305 | DEBIO0932 | DEBIO 0932 | CT-CU305 | CAS [1061318-81-7] | Unfolded protein response (Non selective) | Hsp90 | Inhibitor | Enzymes
2-(6-(Dimethylamino)benzo[d][1,3]dioxol-5-ylthio)-1-(2-(neopentylamino)ethyl)-1H-imidazo[4,5-c]pyridin-4-amine
[1061318-81-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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