NFATc1 inhibitor A04

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3909

CAS [1912422-56-0]

MF C13H8F2INO2
MW 375.11

  • Purity: 99%
  • Soluble in DMSO and EtOH

NFATc1 inhibitor A04

Description

NFATc1 inhibitor A04 is a potent inhibitor of RANKL-induced osteoclastogenesis and bone resorption, with an IC50 value of 1.57 μM and no significant cytotoxic effects on the viability of RAW264.7 cells. The anti-osteoclastogenic effects of A04 may operate through reducing the RANKL-induced nuclear translocation of NFATc1.

KEYWORDS: NFATc1 inhibitor A04 | Supplier | Osteoclastogenesis inhibitor | A 04 | A-04 | CAS [1912422-56-0] | NFAT | Inhibitor | Transcription Factors | Antiresorptive agent

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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