TAE226 - NVP-TAE226

Based on 60 reference(s) in Google Scholar 8 10 60

Axon 3866

CAS [761437-28-9]

MF C23H25ClN6O3
MW 468.94

  • Purity: 99%
  • Soluble in DMSO



TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and a moderately potent IGF-1R inhibitor (IC50 of 140 nM). TAE 226 was also found to be effective as inhibitor for Pyk2 (with a reported IC50 of 3.5 nM) and insulin receptor (InsR) (with a reported IC50 of 44 nM). Furthermore TAE226 was also found to induce apoptosis.

KEYWORDS: TAE226 | Supplier | FAK and IGF-1R inhibitor | NVP-TAE226 | TAE-226 | TAE 226 | NVP-TAE-226 | NVP-TAE 226 | CAS [761437-28-9] | Non Selective (Phosphorylation substrates) | FAK | IGF-1R | Inhibitor | Enzymes

Size Unit Price Stock
5 mg €110.00 In Stock
25 mg €380.00 In Stock
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Size Unit Price Stock
2 x 5 mg €180.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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