I-BET726 - GSK1324726A

Based on 17 reference(s) in Google Scholar 8 10 17

Axon 3860

CAS [1300031-52-0]

MF C25H23ClN2O3
MW 434.91

  • Purity: 99%
  • Optical purity: 99%
  • Soluble in DMSO and EtOH

I-BET726

Description

I-BET726 is a potent and selective, tetrahydroquinoline-based small molecule ligand binding to BET proteins with IC50s (FRET) of 7.4, 7.1, 7.0, and 7.3 nM for BRD2, BRD3 BRD4 and BRDT, respectively, showing no binding potency towards other proteins.

KEYWORDS: I-BET726 | Supplier | BET proteins inhibitor | GSK1324726A | GSK-1324726A | GSK 1324726A | CT-BET726 | CAS [1300031-52-0] | Histone | BET (BRD) | Inhibitor | Proteins

Potent and selective, tetrahydroquinoline-based small molecule ligand binding to BET proteins

Chemical name

4-((2S,4R)-1-Acetyl-4-(4-chlorophenylamino)-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl)benzoic acid

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[1300031-52-0]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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