NUC-1031 - Acelarin

Based on 12 reference(s) in Google Scholar 8 10 12

Axon 3858

CAS [840506-29-8]

MF C25H27F2N4O8P
MW 580.47

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO



NUC-1031 is a phosphoramidate ProTide, and a pro-drug of anticancer nucleoside analog Gemcitabine (Axon 3233). NUC-1031 is a first-in-class nucleotide analogue using phosphoramidate chemistry to enhance anti-cancer efficacy.

KEYWORDS: NUC-1031 | Supplier | DNA synthesis inhibitor | Acelarin | NUC1031 | NUC 1031 | CT-NUC1031 | CAS [840506-29-8] | DNA-RNA | DNA synthesis | Inhibitor | Unclassified

DNA synthesis inhibitor

Chemical name

(2S)-Benzyl 2-((((2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate

Source information

Sold in collaboration with Chemietek

Parent CAS No.


The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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