Based on 34 reference(s) in Google Scholar 8 10 34

Axon 3852

CAS [1088965-37-0]

MF C32H38ClN5O4
MW 592.13

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO



GSK-923295 is a first-in-class high affinity antimitotic inhibitor of centromere-associated protein E (CENP-E), potently and allosterically inhibiting CENP-E ATPase activity with a Ki value of 3.2 nM. Display a broad-spectrum antiproliferative activity against a range of human tumor xenografts grown in nude mice, including models of colon, breast, ovarian, lung and other tumors.

KEYWORDS: GSK923295 | Supplier | CENP-E Inhibitor | GSK-923295 | GSK 923295 | CT-GSK923 | CAS [1088965-37-0] | Microtubules | CENP-E | inhibitor | Enzymes

Allosteric inhibitor of centromere-associated protein E (CENP-E)

Chemical name


Source information

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Parent CAS No.


The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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