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Axon 3852
CAS [1088965-37-0]
MF C32H38ClN5O4MW 592.13
GSK-923295 is a first-in-class high affinity antimitotic inhibitor of centromere-associated protein E (CENP-E), potently and allosterically inhibiting CENP-E ATPase activity with a Ki value of 3.2 nM. Display a broad-spectrum antiproliferative activity against a range of human tumor xenografts grown in nude mice, including models of colon, breast, ovarian, lung and other tumors.
KEYWORDS: GSK923295 | Supplier | CENP-E Inhibitor | GSK-923295 | GSK 923295 | CT-GSK923 | CAS [1088965-37-0] | Microtubules | CENP-E | inhibitor | Enzymes
3-Chloro-N-((S)-1-(2-(dimethylamino)acetamido)-3-(4-(8-((S)-1-hydroxyethyl)imidazo[1,2-a]pyridin-2-yl)phenyl)propan-2-yl)-4-isopropoxybenzamide
[1088965-37-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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