ABT-263 - Novitoclax

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Axon 3821

CAS [923564-51-6]

MF C47H55ClF3N5O6S3
MW 974.61

  • Purity: 99%
  • Optical purity: 99% e.e.
  • Soluble in DMSO
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ABT-263

Description

ABT-263 is a potent, selective and orally bioavailable inhibitor of B-cell lymphoma-2 (BCL-2) family proteins, binding potently to both BCL-2 and BCL-XL with Ki values of <1 nM.

KEYWORDS: ABT-263 | Supplier | Inhibitor of BCL-2 protein | Novitoclax | ABT263 | ABT 263 | CAS [923564-51-6] | Non Selective | Bcl | Inhibitor | Proteins

Potent, selective and orally bioavailable inhibitor of B-cell lymphoma-2 (BCL-2) family proteins

Chemical name

(R)-4-(4-((2-(4-Chlorophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)piperazin-1-yl)-N-(4-(4-morpholino-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[923564-51-6]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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