Oxaprozin is an orally active, nonselective COX inhibitor with IC50 values of 2.2 μM and 36 μM for COX-1 and COX-2, respectively. Moreover, Oxaprozin is capable of inhibiting both anandamide hydrolase in neurons (IC50 value of 85 μM), with consequent potent analgesic activity, and NF-κB activation in inflammatory cells (IC50 value of 50 μM).

KEYWORDS: Oxaprozin | Supplier | COX inhibitor | WY21743 | Oxaprozinum | WY 21743 | WY-21743 | CAS [21256-18-8] | [87240-44-6] | [174064-08-5] | Fatty acid (Arachidonic acid) | COX | Inhibitor | Enzymes | NSAID