Icaritin - Anhydroicaritin

Based on 345 reference(s) in Google Scholar 8 10 345

Axon 3811

CAS [118525-40-9]

MF C21H20O6
MW 368.38

  • Purity: 98%
  • Soluble in 0.1N NaOH(aq), DMSO and EtOH



In hematological malignancies, the exogenous phytomolecule Icaritin showed multiple cytotoxic effects to induce apoptosis, arrest the cell cycle, inhibit proliferation, promote differentiation, restrict metastasis and infiltration, and suppress the oncogenic virus. The proved underlying mechanisms of the cytotoxic effects of Icaritin are different in various cell types of hematological malignancies but associated with the critical cell signal pathway, including PI3K/Akt, JAK/STAT3, and MAPK/ERK/JNK. Also, Icaritin promoted osteogenic but inhibited adipogenic differentiation of mesenchymal stem cells by regulating osteogenesis and adipogenesis related gene expressions.

KEYWORDS: Icaritin | Supplier | Natural flavonoid | Anhydroicaritin | CAS [118525-40-9] | Hematological Malignancies | Leukemia | Lymphoma | Multiple myeloma

Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €330.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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