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Axon 3807
CAS [1640247-87-5]
MF C22H17ClFN9OMW 477.88
GS-9901 is an orally active, potent and isoform-selective inhibitor of PI3Kδ (PI3Kδ IC50 = 1.0 nM, HWB δ EC50 = 1.5 nM; CLpr hHep = 0.05 L/h/kg.), and a potential immunomodulating agent. It is highly selective against other isoforms: p110α (750 nM), p110β (100 nM) and P110γ (190 nM).
KEYWORDS: GS-9901 | Supplier | PI3Kδ inhibitor | GS9901 | GS 9901 | CT-GS9901 | CAS [1640247-87-5] | Phosphatidylinositol | PI3K | Inhibitor | Enzymes
(S)-2,4-diamino-6-((5-chloro-8-fluoro-4-oxo-3-(pyridin-3-yl)-3,4-dihydroquinazolin-2-yl)(cyclopropyl)methylamino)pyrimidine-5-carbonitrile
[1640247-87-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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