Voruciclib - P1446A-05

Based on 5 reference(s) in Google Scholar 8 10 5

Axon 3801

CAS [1000023-04-0]

MF C22H19ClF3NO5
MW 469.84

  • Purity: 99%
  • Optical purity: 99%
  • Soluble in DMSO
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Voruciclib

Description

Voruciclib (P1446A-05) is an oral,potent and selective CDK inhibitor, blocking CDK9, the transcriptional regulator of MCL-1, with sub nanomolar potency, and suppressing MCL-1 expression in cell-based and xenograft models of DLBCL.

KEYWORDS: Voruciclib | Supplier | CDK9 inhibitor | P1446A-05 | P-1446A-05 | P 1446A-05 | P1446A05 | CT-VORU | CAS [1000023-04-0] | DNA-RNA | CDK9 | Inhibitor | Enzymes

Inhibitor of CDK9

Chemical name

2-(2-chloro-4-(trifluoromethyl)phenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-chromen-4-one

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[1000023-04-0]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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