Your cart

There are no items in your shopping cart

PF-06855800

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 3798

CAS [1989620-04-3]

MF C17H16ClFN4O4
MW 394.78

  • Purity: 99%
  • Optical purity: 99
  • Soluble in DMSO

PF-06855800

Description

PF-06855800 is a SAM-pocket-binding (SAM competitive) PRMT5 inhibitor with high selectivity and affinity (PRMT5-MEP-50, Ki < 0.1 nM) and demonstrates robust and efficacious antiproliferative activity in both in vitro and in vivo models.

KEYWORDS: PF-06855800 | Supplier | PRMT5 inhibitor | PF06855800 | PF 06855800 | CT-PF0685 | CAS [1989620-04-3] | Axon Medchem | Axon 3798 | Non Selective (Arginine sites proteins) | PRMT | Inhibitor | Enzymes

SAM-pocket-binding (SAM competitive) PRMT5 inhibitor

Chemical name

(2R,3R,4S,5R)-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-(4-chloro-3-fluorophenyl)(hydroxy)methyl)tetrahydrofuran-3,4-diol

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[1989620-04-3]

Related Products

Axon ID Name Description From price
2709 CMP5 Inhibitor of PRMT5 €95.00
2710 HLCL65 hydrochloride Inhibitor of PRMT5 €105.00
2831 EPZ 015666 Potent, selective and orally available inhibitor of PRMT5 €125.00
3692 PF-06939999 dihydrochloride SAM competitive PRMT5 inhibitor Inquire
3750 GSK3326595 Orally active, potent, selective, SAM uncompetitive, peptide competitive, slow binding inhibitor of protein arginine methyltransferase 5 (PRMT5) Inquire
3754 JNJ-64619178 dihydrochloride SAM-pocket binding (SAM Competitive) PRMT5 inhibitor Inquire
3796 MRTX1719 hydrochloride Inhibitor of the PRMT5.MTA complex Inquire
3919 GSK3368715 hydrochloride A first-in-class, orally active, potent and selective, SAM-Noncompetive inhibitor of Type I Protein Arginine Methyltransferases (PRMTs) Inquire

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Newsletter
Give Feedback
 
Send E-mail

Customer Support

About Axon Medchem

Download Product Catalog

Download the Axon Ligands™ catalogue 2021 Spring Edition

Follow Us

© 2016 Axon Medchem. All Rights Reserved.

Send us a message

×

Contact Us

* Required Fields

Please wait...